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Eur J Heart Fail 2013;15:194-202.ArticlePubMed 19

Conversion of calcidiol to its biologically active form, calcitriol, occurs through the activity of a specific 25-hydroxyvitamin D 3 1--hydroxylase (commonly just called 1--hydroxylase) present in the inner mitochondrial membrane of cells of the proximal convoluted tubules of the kidneys, and in several extrarenal sites such as in keratinocytes, macrophages, and placenta

Rotroff, J

Evidence also indicates that cessation efforts improve both patient and graft survival, highlighting the need for comprehensive smoking cessation programs and supportive measures within transplant centers [113]