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Here we show morphine-induced constipation is mediated by a neural circuit from glutamatergic neurons in the paraventricular nucleus of hypothalamus (PVN Glu ) to acetylcholinergic neurons in the dorsal motor nucleus of the vagus (DMV Ach ), and subsequently to the small intestine in mice

Historical Background and Scientific Context Scientific interest in metabolic regulatory compounds has expanded significantly with advances in molecular biology and biochemical research

B12 medicines contain cobalt, and the MHRA advises extra vigilance for sensitivity reactions in people with known cobalt allergy.Always tell your clinician about allergies before treatment

Under physiological conditions, cellular iron homeostasis is regulated through iron uptake, storage and export