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The glutamate N -methyl-D-aspartate receptor (NMDAR) antagonist ketamine was recently repurposed as a rapidly acting antidepressant, catalysing the vigorous investigation of glutamate-signalling modulators as novel therapeutic agents for depressive disorders

Cycloastragenol reduces inflammation in CLP-induced septic MICE by suppressing TLR4 signaling pathways

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These findings have been cited in support of further research into their use in the context of age-related diseases and active longevity for individuals over 60