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1988 Oct 10;238(2):343-6., Stimulation of collagen synthesis in fibroblast cultures by the tripeptide-copper complex glycyl-L-histidyl-L-lysine-Cu2+ Disease Management and Clinical Outcomes 1(4):136-141 July 1998, Effects of topical creams containing vitamin C, a copper-binding peptide cream and melatonin compared with tretinoin on the ultrastructure of normal skin - A pilot clinical, histologic, and ultrastructural study Arch Pharm Res

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The thread connecting all of these terms is the same loop that runs through PCOS overall inflammation generates oxidative stress, oxidative stress worsens insulin signaling, worsening insulin signaling drives androgen excess, and the cycle reinforces itself