Potential Risks and Side Effects of Synthetic HGH The Endocrine Society notes several concerns with synthetic HGH therapy, particularly when used for anti-aging purposes rather than true medical deficiency: Fluid retention and edema (swelling in hands and feet) Joint pain and muscle aches Carpal tunnel syndrome Increased insulin resistance and potential diabetes risk Gynecomastia (enlarged breast tissue in men) Potential acceleration of existing cancers (though not proven to cause cancer) Suppression of natural pituitary function These side effects typically occur because synthetic HGH provides constant, unregulated hormone levels rather than the natural pulsatile (rhythmic) secretion your body is designed to produce
In one embodiment, when one or more buffers are utilized in the formulations of the present disclosure, they are combined, e.g., with a pharmaceutically acceptable vehicle and are present in the final formulation, e.g., in an amount ranging from about 0.1% to about 20%, from about 0.5% to about 10%
There have been several proteins that have been classified as NTFs based on the effects they have on neuronal survival, differentiation, maturation of electrophysical properties, and plasticity
Transgenic mice expressing the human growth hormone gene provide a model system to study human growth hormone synthesis and secretion in non-tumor-derived pituitary cells: differential effects of dexamethasone and thyroid hormone
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