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Tangeretin (TAN), extracted from tangerine peels , is the primary bioactive component found in traditional Chinese herbs

In studies of brain injury models, overexpression of GPX1 can improve spatial learning ability after brain injury in young mice compared with wild-type mice, possibly due to overexpression of GPX1, which reduces oxidative damage in mice at an early stage (Tsuru-Aoyagi et al., 2009)

SFN, at a daily dosage ranging from 10 to 50 mg/kg, effectively avoided memory deterioration commonly associated with NDs (17)