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It bypasses first-pass hepatic metabolism which oral delivery does not allowing a greater proportion of the absorbed peptide to remain intact as it enters circulation.7 The olfactory pathway also provides a potential direct nose-to-brain route, bypassing the blood-brain barrier a property that has generated interest for neuropeptides and potential neurological applications

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CagriSema's 20.4% mean weight loss on ITT analysis (22.7% on-treatment) means: ~60% of participants lost 20% body weight

93% noticed results the next day after their first Micro-Infusion treatment