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(2021) conducted the only human study on BPC-157 for joint pain

In neuronal senescence model studies, the active ingredient of the product can cross the blood-brain barrier (and act directly on neurons in vitro), increase NAD+ levels in nerve cells, protect mitochondrial function, reduce neuronal apoptosis, and promote the synthesis and release of neurotransmitters (such as dopamine and acetylcholine), thereby improving signal transduction in nerve cells

Cells were seeded at 40 10 3 /well density onto a 96-well ImageLock tissue culture plate to reach a maximum density of 100% and incubated overnight in standard growth conditions

UniProt: the Universal Protein Knowledgebase in 2023