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A PubMed-indexed study on GLP-1R agonist design used in vitro and in vivo assays to compare signaling characteristics against Semaglutide as a reference compound

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The design of isoform- and hepatocyte-specific THR modulators offers a mechanistic basis for liver-targeted antifibrotic therapies, aiming to optimize efficacy while minimizing systemic adverse effects ( In clinical studies, Resmetirom (MGL-3196), the first THR agonist approved by the U.S