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While its ability to influence multiple pathways of repair is supported by compelling preclinical data, the absence of high-quality human trials, the FDAs strict regulatory stance, and the risk of contamination from unregulated sources raise serious safety and legal concerns (including malpractice concerns and fines)

Prager et al., 2015

They play a crucial role in regulating various biological processes, including hormone production, immune function, and tissue repair

As previously described, the fundamental characteristics of ferroptosis include iron overload, GSH depletion, GPX4 inactivation, and lipid peroxidation