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Their low toxicity, bioactivity, and ability to penetrate fungal cell walls make them ideal for addressing superficial fungal infections, particularly onychomycosis (nail infections)

Most recently, a randomized, double-blind, placebo-controlled trial in 81 children (8-14 years) residing in the UK found that use of a daily multivitamin/mineral supplement, containing most vitamins as well as iron, copper, zinc, calcium, and magnesium, was associated with an increase in accuracy on one attention task (Arrows Flankers test) throughout the 12-week study (106)

Studies comparing delivery methods show topical formulations achieve only a fraction of the bioavailability that subcutaneous injection provides

Additionally, insulin facilitates the transport of tryptophan into the brain, which is an essential precursor for melatonin synthesis [139]