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Biochim Biophys Acta (2013) 1832(4):52741

This dramatic increase in weight reduction capabilities naturally leads to speculation around additional health benefits for multiple conditions, including diabetes, cardiovascular, sleep apnea, and others for which medical devices and procedures are often part of management and treatment regimens

Disruption of its function has been identified in several neurodegenerative diseases, including Alzheimer's, Parkinson's, Huntington's, and prion diseases, as well as in amyotrophic lateral sclerosis (ALS)