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Description

PT-141 (alternatively, bremelanotide) is a synthetic cyclic heptapeptide that emulates the function of -melanocyte stimulating hormone (alpha-MSH), a hormone mainly secreted by the pituitary gland [1]

had a run-in period before randomization and withdrew all OADs excluding metformin at the start of the run-in phase ( Table 1 Outlines of the included studies