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Frieboes et al

Another cohort study examined tirzepatide compared to semaglutide and found the absolute difference in weight loss between the two to be 4.3% at six months and 6.9% at 12 months, meaning tirzepatide led to 4.3-6.9% greater weight loss overall

When to be concerned: Sodium imbalances become serious when they cause confusion, severe weakness, or (in extreme cases) seizures

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