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High performance liquid chromatography, reverse transcription-quantitative polymerase chain reaction, and Western blotting revealed that intravenous BMSC application increased the levels of 5-oxoproline and GSH in MCAO rats, as well as the expression of key enzymes involved in GSH synthesis including, gamma-glutamylcyclotransferase and gamma-glutamylcysteine ligase

Lalanne, S

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Consistent with these in vivo results, vitamin K1 treatment impeded RSL3- or erastin-induced ferroptosis by not only regulating GPX4 expression but also modulating the levels of FSP1 and DHODH, two newly identified factors that defend against ferroptosis [114]