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It is commonly studied where peptide signaling, cytoskeletal activity, and cellular migration are evaluated together under conditions of mechanical stress or localized disruption

However, the expansion of pathogenic bacteria can break down this barrier, leading to leaky gut and increasing the risk of pathogens entering the lamina propria and bloodstream [33,34,35]

The BPC-157 peptide is documented in peer-reviewed literature as acting through at least two distinct, non-redundant molecular pathways simultaneously which may explain its unusually broad tissue-repair activity profile

Ethics statement The animal study was approved by Agricultural University of Hunans biomedical research ethics committee (No: 2023096)