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Abstract Advanced maternal age is a key factor in female infertility, primarily due to declines in ovarian reserve and oocyte quality

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Furthermore, since the instability of Ala 2 is caused by degradation of DPP-4, Ala 2 may not need to be changed if the peptide is fused with albumin or Fc domain (discussed later) for long-term activity, which creates a steric hindrance to prevent the enzyme from getting close

Buckley ST, Bkdal TA, Vegge A et al (2018) Transcellular stomach absorption of a derivatized glucagon-like peptide-1 receptor agonist