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Acknowledgements We are grateful to University College Dublin for providing plasma, serum and urine samples for this study

Large reports have shown mitochondrial dysfunction is closely related to the progression of kidney diseases (Zhang et al., 2021a)

Acta biochimica biophysica Sinica 55 (8), 12131221

The primary endpoints are retatrutide's own AUC from time zero to infinity and its maximum observed concentration, sampled from predose out to 31 days