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Simultaneously, ferroptosis may be involved in the progression of cardiac autonomic neuropathy (DCAN) through the P2Y14 receptor (a new member of the metabolic receptor family), while P2Y14 targeting naringin can alleviate DCAN by promoting the NRF2-GPX4 pathway to eliminate ROS and inhibit ferroptosis (117) ( Figure 2 )

Sulphonylureas and insulin usage, for instance, can elevate the possibility of low blood glucose, while gain in weight is commonly observed with insulin, sulphonylureas, and thiazolidinediones

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