A small observational study reported that a brief period of fasting alone improved the signs and symptoms of psoriasis [18], and a 4 week low-energy diet improved the clinical severity of psoriasis independent of changes in weight loss [19]
In a follow-up publication the next year, the Copenhagen group evaluated their isolated GLP-1 (736), along with synthetic GLP-1 (736) amide 4 from a commercial source, and reported modest (two to four-fold) increases in insulin production in the perfused pig pancreas when exposed to nanomolar concentrations of these peptides [45], a significant but less dramatic effect than the earlier MGH findings in rats [40]
10.1038/s41386-019-0531-4 [DOI] [PMC free article] [PubMed] [Google Scholar] Zorrilla, E
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