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Mechanism Summary Table Microbial diversity is not limited to the gut alone

Mitochondrial glutamate is then metabolized by glutamate-oxaloacetate transaminase 2 (GOT2) to -ketoglutarate (2-oxglutarate), which can then be exported back into the cytoplasm in exchange for malate using the SLC25A11 2-oxoglutarate carrier and transaminated back into glutamate by glutamate-oxaloacetate transaminase 1 (GOT1) to continue the MAS

In contrast, in orientation 2, HQ is positioned similarly to L-tyrosine in the active site (Fig