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Ipamorelin, CJC1295 and semorelin are 3 peptides that have an excellent record of safety and effectiveness

The peptide works through several mechanisms: it upregulates growth factor expression (particularly VEGF), promotes angiogenesis (the formation of new blood vessels at injury sites) [5,12] , modulates the nitric oxide system, and supports the FAK-paxillin pathway, which governs cell migration to damaged tissue

Where the molecules triple mechanism might differ from single or dual agonists on safety is one of the open questions, not a settled one