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Statements Data availability statement The original contributions presented in this study are included in this article/supplementary material, further inquiries can be directed to the corresponding author

Adiponectin provides protective metabolic signaling and declines with adiposity, lifting a brake on inflammation and insulin sensitivity that then affects estrogen and progesterone homeostasis

[3] Oral administration is the most pharmacologically unusual option and the one with the strongest theoretical support for gut-specific applications

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