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Statistical analyses As Pearson correlation coefficients between the nine metabolite concentration values (three metabolites in three voxels) were substantial even after adjustment for potential confounders, we used principal component analysis (PCA) to identify latent metabolite variables, and extracted scores for each component (see Results and SA7 for details)

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The CBCL is an instrument used to rate a child's problem behaviors and competencies ( Glutathione Measurements Intracellular reduced, oxidized and total glutathione levels were assessed in blood cells from treatment and control samples collected during weeks 0 (baseline) and week 12 (follow-up)

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