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Insulin Resistance: From Mechanisms to Therapeutic Strategies Article information Abstract Insulin resistance is the pivotal pathogenic component of many metabolic diseases, including type 2 diabetes mellitus, and is defined as a state of reduced responsiveness of insulin-targeting tissues to physiological levels of insulin

Specifically, sermorelin is the smallest GHRH fragment and possesses the bioactive sequence responsible for evoking the secretion of growth hormone (GH) from the anterior pituitary gland [1, 2]

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This peptide can also be referred to as a hormone secretagogue. This means that it is not a hormone by itself and does not replace your bodys production of the growth hormone