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Autoimmune demyelinating disease models (e.g., MS): By dampening inflammatory processes involved in myelin damage, TB500 Fragment (1723) has been proposed as a tool to study prevention of demyelination and relapse dynamics in multiple sclerosislike models

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(B) Similar but more pronounced expression profiles were seen at 18 h in both strains

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Similarly, earlier studies led by Sikiric and colleagues in the 1990s suggested safety and benefit in gastrointestinal conditions such as ulcerative colitis, but these reports were published only in abstracts or local conference proceedings, with no independent replication or peer-reviewed validation

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