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Similar content being viewed by others Introduction Burning Mouth Syndrome (BMS) is a chronic, idiopathic pain disorder characterized by persistent intraoral burning or dysesthetic sensations lasting for more than two hours per day for at least three months, in the absence of clinically detectable mucosal abnormalities or identifiable pathological lesions 1,2

It has a strong growth hormone releasing potency, which can stimulate insulin release from the pancreas in both normal and diabetic rats [3]

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Human Glutaminyl Cyclase has been isolated from nerve tissue, and detected in cerebrospinal fluid and saliva