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Metformin does not directly burn fat cells, but medical studies suggest it helps reduce visceral fat (the dangerous fat stored around the abdomen/belly)

Most evidence of erectile improvements comes from Melanotan 2 studies

Mechanosensitive ion channels may also be involved in the early embryo-uterus crosstalk, as suggested by the high functional expression of the mechanosensitive PIEZO1 channels in epithelial cells of both mouse and human endometrium [40]