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in addition to its crucial role in maintaining genomic stability and regulating inflammation, SIRT6 also directly deacetylates NAMPT, enhancing its activity and promoting NAD + synthesis via the salvage pathway

10.3389/fphar.2021.632295 Summary Keywords gastric pentadecapeptide BPC 157, primary abdominal compartment syndrome, rats, brain edema, lung edema Citation Tepes M, Gojkovic S, Krezic I, Zizek H, Vranes H, Madzar Z, Santak G, Batelja L, Milavic M, Sikiric S, Kocman I, Simonji K, Samara M, Knezevic M, Barisic I, Lovric E, Strbe S, Kokot A, Sjekavica I, Kolak T, Skrtic A, Seiwerth S, Boban Blagaic A and Sikiric P (2021) Stable Gastric Pentadecapeptide BPC 157 Therapy for Primary Abdominal Compartment Syndrome in Rats

J., Howden, R

Mitigation strategies include diluting shots with additional bacteriostatic water or mixing with BPC-157, which reportedly reduces injection discomfort