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In one 4-year real-world study of over 800 adults, participants achieved sustained weight loss of 713%, with greater adherence linked to larger and more cost-effective results, demonstrating a viable, nonpharmacologic pathway for long-term success

The metabolic dysfunction accompanying obesity affects brain function in multiple ways

Aiming for at least 100 grams of protein and 30 grams of fiber per day, plus drinking at least 64 ounces of water will protect lean muscle mass and reduce unwanted side effects while losing weight

The CD38/NAD/SIRTUIN1/EZH2 axis mitigates cytotoxic CD8 T cell function and identifies patients with SLE prone to infections