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For cell treatment by APAP precursors, HepaRG cells and primary human hepatocytes were first incubated with 50 g/ml of APAP or APAP-cys in the maintenance medium described above, during 0.5 h, 2 h, 6 h, 24 h, or 48 h, to optimize the incubation time required to detect APAP metabolites

Feb 15: EMD Serono, a Merck KGaA company, got a win Thursday as the FDA converted Tepmetkos February 2021 accelerated nod to full approval for adult non-small cell lung cancer (NSCLC) patients whose disease harbors mesenchymal-epithelial transition (MET) exon 14 skipping alterations

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