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Volcano plots of the fold change in mitochondrial metabolite abundance (log 2 ) vs P values (-log) from HEK-293T SLC25A39 knockout cell line expressing a vector control or SLC25A40 cDNA
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Without that fuel, microbial diversity declines, beneficial species lose their competitive advantage and short-chain fatty acid production, including butyrate, which maintains the gut lining, drops
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Several possible mechanisms have been conceived for the favorable impacts of synbiotics supplementation on anthropometric indices, mediated through the complementary/synergistic effects of their pro- and prebiotic compartments (24, 38)
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