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This central action drastically decreases sympathetic outflow from the central nervous system to the heart, kidneys, and peripheral vasculature (Figure 1)(Patel and Saadabadi, 2025)

coli expression strain B834 (Novagen) carrying expression plasmids with the gene hoc or soc in the N-terminal or C-terminal fusion with affinity tags

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Shah A, Levesque K, Pierini E et al (2018) Effect of sitagliptin on glucose control in type 2 diabetes mellitus after Roux-en-Y gastric bypass surgery