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Ethics declarations Competing Interests Financial interests: Jaewang Lee and Hyun Jin Park are employed by Logsynk Ltd

Vitamin D: Supports ovarian health and menstrual cycle regulation, as well as being important during pregnancy

Challenges Clinical trials testing the effect of oral arginase inhibitors on endothelial function are currently not available, due perhaps to the fact that most oral formulations of arginase inhibitors have poor oral bioavailability (Pudlo et al., 2017)