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adult obesity rate was a record-high 39.9%, while in 2025, that rate gradually declined to 37%

The result is reduced potency and potentially altered pharmacokinetics

Both medications carry similar serious risks: Thyroid C cell tumors (boxed warning), acute pancreatitis, hypoglycemia (low blood sugar), acute kidney injury and allergic reactions

It has been a very effective medication for lowering blood sugar for many years, with the added benefit of weight loss .[1] In response to the weight loss seen in patients with type II diabetes, Novo Nordisk sent semaglutide into FDA trials for approval as a weight loss medication