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Signs and symptoms: Many common symptoms can be caused by vitamin B12 deficiency, including weakness, tiredness, lightheadedness, heart palpitations, shortness of breath, pallor (pale skin), diarrhea, decreased appetite, nerve problems like numbness or tingling, visual changes and psycho-emotional problems like depression, memory loss or behavioral changes

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The food supplement should not be used as a meal replacement

A meta-analysis study including a cohort of 184,024 people and 351 cases of incident PD found that pre-diagnostic caffeine, along with its primary metabolites paraxanthine and theophylline, were associated with a reduced risk of PD