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Liraglutide (Injectable) Shows More Promise The ELAD Phase 2b trial of injectable liraglutide in mild Alzheimers disease showed more encouraging signals: brain volume loss in memory-related regions was reduced by nearly 50% compared to placebo over one year

Pharmacology & Therapeutics

In patients diagnosed with anxiety or bipolar disorder, it could stabilize mood and improve cognitive response to stress

However, currently the use of GLP-1 RAs is not recommended as treatment of MASLD.(3) The American Diabetes Association 2025 guidelines similarly state GLP-1 RAs are recommended in adults with diabetes, obesity, and MASLD in combination with diet and exercise for weight loss