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In this work deletion of glgB encoding GBE was expected to shut down glycogen accumulation

Combining AITC with the glutathione biosynthesis inhibitor L-buthionine-sulfoximine (BSO) led to an even stronger phenotype than observed for the single treatments

Recommended Monitoring Timeline: 3 months: HbA1c, lipids 6 months: full metabolic panel What to Track: Glycemic improvement Lipid changes Liver enzymes Nutritional markers Cost, Accessibility, and Practical Considerations Access to testing varies globally, but most core labs are widely available