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The proposed fat loss mechanism operates through SAM and NAD+ preservation

3.4 Dietary iron intake and IBD Iron deficiency anemia is a prevalent complication in patients suffering from IBD, and iron replacement therapy (IRT) can improve anemia, including oral and intravenous iron supplementation, but iron overload can lead to ferroptosis (68)

The carnitine shuttle system is a key regulator of ferroptosis in cancer cells, and dysfunction of the carnitine cycle in general can influence tumorigenesis and progression of the disease by altering intracellular oxidative and inflammatory status or regulating tumour metabolism

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