Cal LA, Pagnin E, Davis PA, Semplicini A, Nicolai R, Calvani M, Pessina AC (2006) Antioxidant effect of L-carnitine and its short chain esters: relevance for the protection from oxidative stress related cardiovascular damage
Acetoacetate can take two paths: it can undergo non-enzymatic decarboxylation, resulting in the production of acetone, or it can be converted to HB via the enzyme HB dehydrogenase, as mentioned by Dhillon and Gupta (2023)
These include longer recovery with downtime, post-inflammatory hyperpigmentation (especially in darker skin types), infection, scarring, and prolonged erythema
These candidates demonstrate clinical differentiation and innovation, moving beyond traditional biosimilar or fast-follower strategies