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Unfortunately, we were unable to harvest sufficient A2780DPP/GSTP1 knockdown cells to perform western blotting, cytotoxicity assays or more detailed phenotypic characterisation, but our confirmation of GSTP1 knockdown, together with selective platinum toxicity in puromycin-resistant clones is consistent with an essential role for GSTP1 in glutathione conjugation and cisplatin detoxification

[DOI] [PubMed] [Google Scholar] 28.Kojer K, Bien M, Gangel H, Morgan B, Dick TP, Riemer J: Glutathione redox potential in the mitochondrial intermembrane space is linked to the cytosol and impacts the Mia40 redox state: E GSH of the IMS is maintained by the cytosol

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Oral, Liposomal, S-Acetyl, IV and Precursors Are Dietary Supplements Really Unregulated