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The immunopathology of multiple sclerosis: an overview

Inflammation Modulation Unlike NSAIDs, which blunt inflammation indiscriminately, BPC-157 appears to reduce pro-inflammatory signalling while preserving the inflammatory response necessary for healing, a pattern summarized across the preclinical literature in a 2025 narrative review of BPC-157 for musculoskeletal healing McGuire et al

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For instance, while electrical stimulation of the cerebellar cortex may have activated Purkinje cell output to the deep cerebellar nuclei (and may, thus, have had produced inhibitory effects in brain areas receiving cerebellar output), recent studies have suggested that at least some forms of TMS of the cerebellum (e.g., continuous theta-burst stimulation) lead to reduced cerebellar activity ([306]