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December 2025: Ascletis Pharma announced that ASC30, an oral small-molecule GLP-1 receptor agonist, demonstrated 7.7% placebo-adjusted weight loss in a 13-week U.S

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Safety, tolerability, pharmacokinetics, and pharmacodynamics of concomitant administration of multiple doses of cagrilintide with semaglutide 2.4 mg for weight management: A randomised, controlled, phase 1b trial

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