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Use of synthetic IGF-1 analogs is prohibited at all times due to their performance-enhancing potential and influence on growth pathways. WADA Prohibited List, 2024 Legal Status in the United States and Globally Possession for personal research use is not criminalized in most jurisdictionsbut selling, distributing, or marketing IGF-1 peptides for human consumption can lead to regulatory penalties

The WSJ piece touches on many Sinclair longevity firms including Sirtris, CohBar, OvaScience, Life Biosciences, and Tally Health

Differently, in a mouse model of myeloma, arginine depletion by arginase-expressing M2 macrophages is associated with tumor cells starvation and death [18]

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