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Materials and methods Clinical trial design This was a phase Ib, single centre, open-label study (NCT03350191, ClinicalTrials.gov) with 20 days once daily repeated subcutaneous doses of SAR425899 at 2 different dose regimens (A and B) in overweight to obese T2D patients

Another study has investigated the expression profiles of Wnt/-catenin signaling genes in human oocytes, finding that the expression of WNT1 and GSK3 genes was elevated in PCOS patients, while there was no significant difference between the PCOS group and the control group in terms of APC and -catenin expression levels