[88] In March 2026, the CHMP recommended granting a conditional marketing authorization for Kayshild (semaglutide), a GLP-1 receptor agonist for the treatment of non-cirrhotic metabolic dysfunction-associated steatohepatitis (MASH) with liver fibrosis, a serious disease where fat deposits accumulate in the liver causing inflammation
Patients with severe gastrointestinal disease , including gastroparesis, may experience symptom exacerbation due to delayed gastric emptying
[DOI] [PubMed] [Google Scholar] 171.Hasan-Olive M.M., Lauritzen K.H., Ali M., Rasmussen L.J., Storm-Mathisen J., Bergersen L.H
The decision to combine these agents must be individualized based on patient-specific factors, including medical history, current medications, cardiovascular health, and response to previous weight management interventions