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The rationale was not arbitrary
Injections and IV infusions, meanwhile, deliver precise, high systemic levels under professional supervision
Why Oral Bioavailability Is Lower Even though BPC-157 survives gastric acid better than most peptides, oral administration still subjects it to: First-pass metabolism the liver processes a significant portion before it reaches systemic circulation Variable absorption affected by food, stomach pH, and individual GI function Enzymatic degradation some breakdown still occurs in the intestinal tract The result is that oral BPC-157 delivers a lower and less predictable systemic dose compared to injection
The majority of subjects in both groups experienced either no or mild improvement
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