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GLP-1 medications slow stomach emptying and can suppress appetite, making it easy to forget drinking wateryet your body needs more fluids when insulin sensitivity improves and glucose metabolism shifts

That incremental GCGR effect could theoretically be achieved by titrating retatrutide monotherapy instead, without the compounded risk

If you experience persistent side effects at a given dose, your PlexusDx provider may hold your dose steady, reduce it slightly, or switch you to an alternative compound like tirzepatide or oral semaglutide

Here are a few factors you must consider: Concentration: Start with a lower concentration (between 5-10%) and gradually increase it to 1520% L-ascorbic acid