Hirose S, Mitsudome A, Yasumoto S, et al
While Ozempic may always be the generic term for these drugs, just like we ask for Kleenex when we want a tissue, Moore expects that medical providers and researchers will look back 10 or 15 years from new and see Ozempic as a pretty dated drug. There is even talk about people someday getting little implants in their bellies that will gradually release GLP-1s to help control appetite without the need for pills or injections
The rare individual who might consider this combination needs exceptional GI tolerance proven on prior GLP-1s, physician supervision with frequent monitoring, ability to afford $15,000-30,000 annually, understanding they're experimenting on themselves, and willingness to stop immediately if severe side effects emerge
Adjacent human safety: Increlex (mecasermin) FDA label 71 pediatric patients with severe primary IGFD treated for a mean of 3.9 years