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It traces back to Pavlov, who sold dog gastric juice as a remedy, and to Selye's stress work, on the idea that the gut makes its own protective signal

Congenital hypothyroidism: A 20202021 consensus guidelines update-an ENDO-European reference network initiative endorsed by the European society for pediatric endocrinology and the european society for endocrinology

By combining them, researchers can investigate a broader range of biological mechanisms while maintaining consistency across experimental designs

Numerous emerging DHTs, such as next-generation wearable devices, large language models 52 , and digital twins 53 , are expected to revolutionize clinical trial paradigm 54